NI PCI-6224 | 32-Channel Analog Input DAQ Card — Replacement, Equivalent & Selection Guide
The National Instruments PCI-6224 (NI PCI-6224) is a 32-channel, 16-bit, 250 kS/s analog input data acquisition card for the PCI bus. This page is the definitive selection, replacement, and compatibility reference for engineers and procurement teams sourcing the PCI-6224 or a verified equivalent.
Technical Specifications
- Model / SKU: NI PCI-6224
- Manufacturer: National Instruments (NI) / Emerson
- Series: M Series DAQ
- Bus Interface: PCI (32-bit, 33 MHz)
- Analog Input Channels: 32 single-ended / 16 differential
- ADC Resolution: 16-bit
- Max Sampling Rate: 250 kS/s (aggregate)
- Input Range: ±0.1 V to ±10 V (8 programmable ranges)
- Digital I/O: 32 lines (bidirectional)
- Counter/Timers: 2 × 32-bit, 80 MHz timebase
- Analog Output: None
- Connector: 68-pin VHDCI
- Operating Temperature: 0 °C to 55 °C
- Software Support: NI-DAQmx, LabVIEW, LabWindows/CVI, Measurement Studio
- OS Compatibility: Windows 10/11, Windows Server 2016+
Compatible Replacement & Equivalent Models
When the PCI-6224 is discontinued, out of stock, or cost-prohibitive, the following models offer functional equivalence or direct drop-in replacement capability:
- NI PCIe-6321 — PCIe bus upgrade; 16-bit, 250 kS/s, 16 AI, 2 AO. Best for new system builds.
- NI PCI-6221 — Same M Series family; 16 AI, 16-bit, 250 kS/s. Suitable when fewer AI channels suffice.
- NI PCI-6229 — 32 AI, 16-bit, 250 kS/s + 4 AO channels. Direct functional upgrade.
- NI PCI-6251 — Higher throughput (1.25 MS/s); pin-compatible with PCI-6224 accessories.
- NI USB-6212 — USB portable alternative; 16 AI, 16-bit, 400 kS/s. Ideal for field use.
- Measurement Computing USB-1608G — Third-party equivalent; 16 AI, 16-bit, 500 kS/s via USB.
Always verify connector pinout, driver compatibility, and channel count before substitution in production systems.
Why Choose the Original NI PCI-6224
- Proven M Series architecture with decades of field reliability
- Full NI-DAQmx driver support with extensive documentation and community resources
- 32 AI channels in a single PCI slot — maximizes channel density
- Seamless integration with LabVIEW, TestStand, and NI Signal Express
- Calibration certificates available; traceable to NIST standards
- Broad accessory ecosystem: SCC carriers, SCXI modules, terminal blocks (NI TB-2715)
Typical Applications
- Industrial process monitoring and control
- Automated test equipment (ATE) systems
- Vibration and acoustic measurement
- Temperature, pressure, and flow sensor acquisition
- Power electronics characterization
- Research and laboratory data logging
- Machine condition monitoring (predictive maintenance)
System Compatibility
- Bus: PCI slot (3.3 V or 5 V universal)
- OS: Windows 10 (32/64-bit), Windows 11, Windows Server 2016/2019/2022
- Driver: NI-DAQmx 19.0 or later (free download from ni.com)
- Accessories: NI SH68-68-EP cable, NI CB-68LP / CB-68LPR terminal blocks, NI BNC-2110 connector block
- Chassis: Standard desktop PCI slot; not compatible with PCIe-only motherboards without adapter
Selection Guide
| Requirement | Recommended Model |
|---|---|
| 32 AI, PCI bus, legacy system | NI PCI-6224 (this product) |
| 32 AI, PCIe bus, new build | NI PCIe-6321 / PCIe-6341 |
| 32 AI + 4 AO, PCI bus | NI PCI-6229 |
| Higher speed (>250 kS/s), PCI | NI PCI-6251 (1.25 MS/s) |
| Portable / USB-based | NI USB-6212 / USB-6218 |
| Budget-conscious, USB | Measurement Computing USB-1608G |
Quality Assurance & Sourcing
- All units sourced from authorized distributors or verified secondary market suppliers
- Pre-shipment functional testing available on request
- Original NI calibration data and certificates provided where available
- Anti-counterfeit inspection: serial number verification against NI database
- Packaging: ESD-safe anti-static bag, foam-padded carton
- Warranty: 90-day return-to-base warranty on all tested units
How to Order
- Confirm your PCI slot availability and OS version
- Verify required AI channel count and sampling rate
- Select quantity and contact us for bulk pricing
- Submit PO or inquiry to support@konmask.com
- Lead time: typically 3–7 business days for in-stock units
Replacement & Compatibility FAQ
Q: Is the NI PCI-6224 still in production?
A: The PCI-6224 is a mature product. NI (now part of Emerson) may have limited new stock. Konmask.com maintains refurbished and tested inventory.
Q: Can I use the PCI-6224 with a PCIe motherboard?
A: Only if your motherboard has a legacy PCI slot. PCIe slots are not backward-compatible without a PCI-to-PCIe bridge adapter.
Q: What is the difference between PCI-6224 and PCI-6229?
A: The PCI-6229 adds 4 analog output channels (16-bit, 833 kS/s AO) while maintaining the same 32 AI configuration. Choose PCI-6229 if AO is required.
Q: Does the PCI-6224 work with Python?
A: Yes, via the nidaqmx Python package (pip install nidaqmx), which wraps the NI-DAQmx C API.
Q: Can Konmask.com provide a calibration certificate?
A: Yes, calibration certificates are available for recently calibrated units. Please specify at time of order.
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