HPLC Column Temperature Control Solution – Waters 289000192 | Heat/Cooler Engine
The Waters 289000192 Heat/Cooler Engine is a precision thermoelectric temperature control module engineered for Waters HPLC and LC-MS analytical instrument platforms. Cross-referenced as 385150-001, WT-28900-192-A, 289000560, 0140-77637, 0190-37190, 0100-20458, this OEM-grade component maintains column temperature stability critical to chromatographic reproducibility and peak resolution.
Where This Product Is Used
- Pharmaceutical QC & R&D Labs — Column oven temperature control in method validation and stability studies under ICH Q1A/Q2(R1) guidelines
- Bioanalytical & CRO Laboratories — Maintaining isothermal conditions for protein, peptide, and small-molecule separations in LC-MS/MS workflows
- Environmental Testing Labs — EPA method compliance requiring precise column temperature for pesticide, VOC, and contaminant analysis
- Food & Beverage Safety — Mycotoxin, allergen, and additive screening on Waters HPLC platforms
- Academic & Research Institutions — Metabolomics, proteomics, and natural product isolation requiring repeatable retention times
- Chemical & Petrochemical Industry — Purity analysis and process monitoring with temperature-sensitive separations
Technical Specifications
- Part Number: 289000192
- Cross-Reference SKUs: 385150-001 | WT-28900-192-A | 289000560 | 0140-77637 | 0190-37190 | 0100-20458
- OEM Brand: Waters Corporation
- Component Type: Heat/Cooler Engine (Thermoelectric Module)
- Function: Peltier-based heating and cooling for column temperature management
- Compatible Systems: Waters HPLC / UPLC / LC-MS column oven assemblies
- Weight: 700 g
- Condition: OEM Replacement / Refurbished Available
Why Engineers Specify This Model
- Dual-Mode Thermoelectric Control — Supports both active heating and sub-ambient cooling, enabling a wider operating temperature range than passive column ovens
- OEM Dimensional Fit — Drop-in replacement with no mechanical modification required; preserves original instrument geometry and airflow
- Retention Time Reproducibility — Stable column temperature directly reduces run-to-run RT variance, a critical metric in regulated analytical environments
- Multi-SKU Cross-Reference — Sourced under multiple Waters part numbers across instrument generations, ensuring backward compatibility
- Reduced Instrument Downtime — Fast-swap module design minimizes HPLC system downtime versus full column oven assembly replacement
Complete System Bill of Materials
Commonly paired components for a full column temperature control assembly:
- Waters Column Oven Assembly (compatible model-specific)
- Thermoelectric controller PCB / driver board
- Column oven door seal / gasket kit
- Temperature sensor (NTC thermistor or RTD, model-specific)
- Thermal interface pad / heat sink compound
- Wiring harness / connector kit (Waters OEM)
Compliance & Industry Standards
- GMP / GLP Compatibility — Suitable for use in 21 CFR Part 11 regulated laboratory environments when installed per OEM specifications
- ICH Q2(R1) — Supports method validation requirements for precision and reproducibility
- ISO/IEC 17025 — Compatible with accredited laboratory instrument qualification (IQ/OQ/PQ) protocols
- RoHS Compliance — Verify with current lot documentation; available upon request
Quality Assurance & Sourcing
- All units inspected and verified against OEM part number prior to shipment
- Sourced from authorized dismantlers, OEM overstock, or certified refurbishment channels
- Traceability documentation available for regulated laboratory procurement
- Packaging: anti-static, moisture-barrier, with foam cushioning for safe international transit
- Warranty: 90-day functional warranty standard; extended warranty available on request
How to Source This Part
To place an order or request a quote for the Waters 289000192 Heat/Cooler Engine:
- Online: Add to cart directly on this page — stock is limited and updated in real time
- Email RFQ: support@konmask.com — include your instrument model and required quantity
- Phone / WhatsApp: +0086 19859288691 — available for urgent procurement and bulk orders
- Lead Time: In-stock units ship within 1–3 business days; sourced units 5–10 business days
Application-Specific FAQ
Q: Which Waters instruments use the 289000192 Heat/Cooler Engine?
A: This module is used across multiple Waters HPLC and UPLC column oven platforms. Cross-reference your instrument’s service manual with part numbers 385150-001, WT-28900-192-A, or 289000560 to confirm compatibility. Contact us with your instrument serial number for verification.
Q: Is this a new OEM part or refurbished?
A: We supply both new OEM overstock and professionally refurbished units. Condition is specified at checkout. All units pass functional inspection before shipment.
Q: Can this module be used in a GMP-regulated lab?
A: Yes, when installed per Waters OEM service procedures and qualified under your site’s IQ/OQ/PQ protocol. Traceability and lot documentation are available upon request.
Q: What is the typical failure mode for this component?
A: Common failure indicators include inability to reach setpoint temperature, erratic temperature readings, or column oven error codes on the Waters system controller. The Peltier element and solder joints are the most frequent failure points.
Q: Do you offer volume pricing for service centers or distributors?
A: Yes. Contact us at support@konmask.com for distributor pricing, blanket PO arrangements, and consignment stock programs.
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Contact: support@konmask.com | +0086 19859288691
